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In a First, Surgeons Attached a Pig Kidney to a Human — and It Worked
外科医生首次成功将猪肾移植到人身上
Surgeons in New York have successfully attached a kidney grown in a genetically altered pig to a human patient and found that the organ worked normally, a scientific breakthrough that one day may yield a vast new supply of organs for severely ill patients. Although many questions remain to be answered about the long-term consequences of the transplant, which involved a brain-dead patient followed only for 54 hours, experts in the field said the procedure represented a milestone.
纽约外科医生成功地将转基因猪的肾脏移植到人类病人身上,而且发现该器官可以正常工作。这是一项科学突破,有朝一日或许可以为重症病人提供大量新的器官供应。尽管移植手术的长期后果(影响)仍有许多问题有待回答,该移植手术涉及一名脑死亡患者,只持续了54小时,但该领域的专家表示,这一手术是一个里程碑。
Researchers have long sought to grow organs in pigs suitable for transplantation into humans. A steady stream of organs — which could eventually include hearts, lungs and livers — would offer a lifeline to the more than 100,000 Americans currently on transplant waiting lists, including the 90,240 who need a kidney. Twelve people on the waiting lists die each day. An even larger number of Americans with kidney failure — more than a half million — depend on grueling dialysis treatments to survive.
长期以来,研究人员一直试图在猪身上培育适合移植到人体的器官。稳定的器官供应——最终可能包括心脏、肺和肝脏——将为目前在等待移植名单上的10万多美国人提供一条生命线,其中包括90240名需要肾脏的人。每天有12个人在等待名单上死去。更多患有肾衰竭的美国人依靠艰苦的透析治疗来生存,这个人数超过了50万。
The surgery, carried out at N.Y.U. Langone Health, was first reported by USA Today on Tuesday. The research has not yet been peer-reviewed nor published in a medical journal. The transplanted kidney was obtained from a pig genetically engineered to grow an organ unlikely to be rejected by the human body. In a close approximation of an actual transplant procedure, the kidney was attached to a person who had suffered brain death and was maintained on a ventilator.
本周二,《今日美国》(USA Today)首次报道了在纽约大学朗格尼健康中心(NYU Langone Medical Center)进行的手术。这项研究还没有经过同行评审,也没有在医学杂志上发表。移植的肾脏来自一头经过基因工程改造的猪,它能生长出一个不太可能被人体排斥的器官。在与实际移植程序相似的情况下,肾脏被移植到一个靠着呼吸机维持生命的脑死亡的人身上。